My cell bio text says "The anaphase inhibitor, securin, which secures the attachment of sister chromatids is ubiquitinated for destruction which releases separase to cleave a subunit of cohesin which holds the sister chromatids together, which subsequently marks the onset of anaphase." My question is...So what is the actual difference between securin and cohesin? Do they both accomplish the same task of holding the sister chromatids together? Why the need for two completely separated processes of to initiate this?
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